Abstract: The metallogenic belt of the northern margin of the North China Craton is an important rare earth-gold polymetallic metallogenic zone in Northern China, characterized by favorable metallogenic geological conditions and significant exploration potential. The spatiotemporal distribution rules of gold deposits in the metallogenic belt of the northern margin of the North China Craton were summarized in this research, based on the gold ore deposit database. The results revealed a distinct east-west spatiotemporal differentiation. The Hercynian-Indosinian period was the main mineralization epoch in the western segment, and the Yanshanian period was the primary mineralization epoch in the eastern segment. Based on the analysis of ore-controlling factors for different types of gold deposits, 43 ore-controlling factors including geological and geochemical anomalies were collected and analyzed. Besides, 23 predictive factors were identified using the information computation method, leading to the delineation of gold exploration prospect areas within the metallogenic belt. The results showed that 77 prospective areas were identified and classified into three levels: 26 Level Ⅰ, 31 Level Ⅱ, and 20 Level Ⅲ prospective areas. The favorable metallogenic areas that is Wulashan, Wulatezhongqi-Damaoqi, Suniteyouqi-Xianghuangqi, Xindigou, the southern Chifeng, and Jinchanggouliang-Erdaogou in the western Liaoning were delineated through comprehensive analysis, where hosted 22 most critical Level Ⅰ prospective areas, indicating the key targets for future gold exploration in the metallogenic belt of the northern margin of the North China Craton.