Abstract: Jiaodong area of Shandong Province is rich in gold resources and has great ore-forming potential. However, the geological outcrop condition is poor in the southward extension area of Jiaojia fault, which is the main ore-controlling structure, and the deep fault extension is unknown, seriously restricting the progress of ore prospecting. A joint exploration and application study was carried out using high-precision magnetic prospecting, longitudinal intermediate gradient IP profiling and IP sounding in Zhengjia area of Laizhou City in Shandong Province. A three-dimensional geophysical model was established, and a comprehensive interpretation of anomaly areas and metallogenic prediction were carried out, combined with borehole and geological data. The deep electrical structure of the southern section of Jiaojia fault was preliminarily determined to be NE trend, with a slight dip to the east, and the favorable locations for mineralization were middle-shallow tectonic fracture zone and the change site of the fault occurrence. Because gold minerals mainly occur in pyrite, chalcopyrite and quartz, the geophysical prospecting direction should be a tectonic fracture zone with high apparent polarizability anomaly. The feasibility of integrated geophysical prospecting in gold deposit prediction was verified in this paper, and it also could provide some references for the selection of prospecting means under similar geological conditions.