Abstract: In order to find out the distribution of strata, rock, paleontology and Carlin-type gold desposits in Southwestern Guizhou Province, the authors developed the 1:50 000 regional geological survey of Jingnan sheet, Bajie sheet and Pojiao sheet using the new methods of digital geological mapping, modern geological theory and test methods. The results show that the strata graphical units were clarified and divided, and that 18 informal mapping units were established according to rock associations as well as animal and plant fossils. Marine reptile fossils--Ichthyosaurid were first found in shelf facies of late Early Triassic at Northwestern Youjiang Basin. Marine reptile fossils--Nothosaurus were also found in platform-edge reefs facies of Middle Triassic. 11 new mineralization occurrences were discovered, including 9 gold mineralization occurrences, 1 molybdenum mineralization occurrence and 1 collophanite mineralization occurrence. This paper also delineated three metallogenic prospective areas and one target area. The research can provide useful information for geological and mineral investigations and researches in this area.