Abstract: Through the mineral prospecting project in Baiyin mine field and its periphery of Gansu Province, the authors have delineated twelve 1:50 000 aeromagnetic anomaly areas, seven 1:50 000 high magnetic anomaly areas and sixty-four 1:50 000 geochemical prospecting anomaly areas. Besides, four mineral occurrences and six mineralized spots were found, including copper, lead, zinc etc. The temporal and spatial distribution of mineralization and the paragenesis and combination rules of mineral resources were also expounded, after a comprehensive study of the metallogenic geological conditions, 1:50 000 geochemical and geophysical anomalies and the characteristics of mineral occurrence distribution. The “multi-type” prospecting prediction model was concluded in the study area. Nine key metallogenic prospective areas were delineated, including three type A, two type B and four type C prospective areas. Four target prospecting areas were delineated, including one type A, one type B and two type C target prospecting areas.