Abstract: Huaibei area is an important iron-copper metallogenic area in northern Anhui Province. In order to summarize the metallogenic series and regularity of skarn-type deposits systematically in this area, based on recent prospecting results and the diagenesis and metallogenic chronology, the authors systematically investigated the geological characteristics and metallogenic conditions of the known deposits and divided thern into three metallogenic series. They are skarn-type iron-copper-gold metallogenic series related to high-K calc-alkali intrusive rocks, skarn-type iron-gypsum metallogenic series related to high-K calc-alkaline intrusive rocks and skarn-type iron-light rare earth metallogenic series related to monzogranite. Then the geological characteristics and metallogenic regularity of four typical deposits were discussed respectively. The results show that the deposit formation can be divided into two stages in this area, and the metallogenic space is controlled by deep faults, arc structures and magmatic belts. Finally, the regional metallogenic models of Qianchang type, Yangqiaozi type and Wangchang type iron polymetallic deposits in the early stage of Early Cretaceous and Qiganlou type iron-light rare earth deposits in the late stage of Early Cretaceous were established.